Dr. Arnaud Blondel
Dynamics & Drug Design group
Department of Structural Biology and Chemistry
Institut Pasteur
25-28 rue du docteur Roux,
F-75015 Paris
Phone: +33 1 40 61 36 93
arnaud.blondel (at) pasteur.fr

Arnaud Blondel has a background in physical chemistry of proteins and molecular dynamics methods. After a postdoc with Martin Karplus, he joined the Institut Pasteur, where he develops novel methods to grasp the functional mechanisms of proteins with the aim to identify potent binding sites to find novel types of inhibitors along innovative strategies.

  1. Laine, E., Goncalves, C. Karst, J., Lesnard, A., Rault, S., Tang, W-J., Malliavin, T.E., Ladant, D. and Blondel, A. (2010) "Use of allostery to identify inhibitors of calmodulin-induced activation of Bacillus anthracis edema factor" Proc. Natl. Acad. Sci. U.S.A., 107, 11277-11282.
  2. Conti P, Tamborini L, Pinto A, Blondel A, Minoprio P, Mozzarelli A, and De Micheli C. (2011) "Drug Discovery Targeting Amino Acid Racemases" Chem Rev., 111, 6919-6946. DOI: 10.1021/cr2000702 3. Desdouits, N., Nilges, M. and Blondel, A. (2015) "Principal component analysis reveals correlation of cavities evolution and functional motions in proteins." J Mol Graph Model. 55, 13-24.