Alexander Dömling
Professor and Chair
University of Groningen /
Department of Drug Design
School of Pharmacy
Phone: +3150-3633307

FAX: +3150-3637582


Alexander Dömling studied Chemistry & Biology at the Technische Universität München and performed his PhD with the late Prof Ivar Ugi. As a Feodor Lynen stipendiat funded by the Humboldt foundation he spend his postdoc time with Nobel Laureate Barry Sharpless at The Scripps Research Institute. He was professor at the University of Pittburgh and is currently chair of the department of drug design and professor at the University of Groningen. His research interest include the development of computational and experimental techniques of early drug discovery. Dömling is a strong believer in structure-based drug design and is thus working on multiple targets in the area of immune-cancer, inflammation, infectious disease and orphan diseases. He is author of over 200 publications, reviews, books and patent applications. As an innovator and serial entrepreneur he is founder of several biotechnology companies.

Khoury, K., Sinha, M. K., Nagashima, T., Herdtweck, E. and Dömling, A. (2012), Efficient Assembly of Iminodicarboxamides by a “Truly” Four-Component Reaction . Angew. Chem. Int. Ed., 51: 10280–10283. doi: 10.1002/anie.201205366

Czarna, A., Beck, B., Srivastava, S., Popowicz, Grzegorz M., Wolf, S., Huang, Y., Bista, M., Holak, Tad A. and Dömling, A. (2010), Robust Generation of Lead Compounds for Protein–Protein Interactions by Computational and MCR Chemistry: p53/Hdm2 Antagonists. Angew. Chem. Int. Ed., 49: 5352–5356. doi: 10.1002/anie.201001343

Kroon, E., Schulze, J. O., Süß, E., Camacho, C. J., Biondi, R. M. and Dömling, A. (2015), Discovery of a Potent Allosteric Kinase Modulator by Combining Computational and Synthetic Methods. Angew. Chem. Int. Ed.. doi: 10.1002/anie.201506310